Furthermore, increased MID by the extracts could indicate macrophage formation ability and pathogenic scavenging role. Despite the therapeutic importance of medicinal plants, toxic substances have been shown to be present in large numbers of plants investigated [3]. The research work was carried out in collaboration between all authors. READ ALSO: How long does it take for Aju mbaise to work. Joseph, H., Gleye, J., Moulis, C., Mensah, L. J., Roussakis, C., and Gratas, C. Justicidin B, a cytotoxic principle from Justicia pectoralis. 9 health benefits of justicia carnea - Herbconer Blooming from early summer to fall, the flowers are attractive to hummingbirds and butterflies. WBC reduced in rats treated with doses of J. carnea with significant decrease (p<0.05) in rats that received 50, 100 and 1200mg/kg body weight. Google Scholar. Paradoxically, oxidation of GSH has been reported to occur when GSH interact with metal ions thereby generating superoxide anions from the transfer of electrons from the metal ions to molecular oxygen [32]. Safety assessment of oral administration of ethanol extract of Justicia Emmanuel Sina Akintimehin. Anaemia is a common blood disorder that affects people of all ages, though people at greater risk are the elderly, young women and infants. Daily intake of the Ewe eje or ajeri can increase the absorption of iron and vitamins, Uses and health benefits of Ewe eje (Justicia carnea leaf). This is in agreement with previous work on the reversed effect of J. carnea leaf extract on anaemia induced experimental rat [9, 21]. The findings show that ethanol extracts of Costus afer and Justicia carnea could operate as main antioxidants and free radical scavengers. Ashwagandha tea: 10 benefits, side effects and recipes, 7 interesting health facts about Black sapote fruits. Lipid peroxidation was determined by measuring the formation of thiobarbituric acid reactive substances (TBARS) according to the method described by Buege and Aust [20]. The lush foliage and distinctive flowers make Brazilian Plume a natural for a tropical garden. Akintimehin is a lecturer in the Biochemistry unit of Chemical Sciences Department, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. Photomicrograph of a liver sections stained with Haematoxylin and Eosin (Mag. [1] The perennial plant is native to the Atlantic Forest ecoregions of eastern Brazil . The acute toxicity test also proved that justicia carnea leaves are safe for consumption. These tropical plants are not very fussy about soil. Further, 0.5ml of supernatant was treated with 0.5ml of Ellmans reagent (containing 19.8mg of 5,5 dithiobis - (2-nitrobenzoic acid) (DTNB) in 100ml of 0.1% sodium nitrate) and 3.0ml of phosphate buffer (0.2M, pH8.0). In recent time, copious attention has been focused on the use of medicinal plants in the management and treatment of ailments such as anemia, diabetes and malaria. They look terrific in properly shaded outside areas such as porches, patios, driveways, and entryways. It also increases good cholesterol levels. Justicia Carnea; Blood-Boosting Green Plant That Turns Hot Water Red! In conclusion, oral acute administration of J. carnea ethanol extract is safe because neither mortality nor any signs of toxicity were observed in experimental rats. Justicia carnea is commonly cultivated and grown as an ornamental potted plant. Effect of methanol leaf extract of Justicia carnea on serum albumin (ALB) and total protein (TP) concentration CCl 4 intoxicated rats. Watering depends on humidity and temperature. Ewe eje is safe and healthy for consumption. J Nat Prod 1988;51(3):599-600. Ewe eje isnt capable of causing any side or negative effects if consumed moderately. Acute and chronic toxicity of the aqueous extract of Artemisia afra in rodents. Side effects of Ewe eje (Justicia carnea leaf Side Effects). While graded doses of J. carnea ethanol extract showed no significant difference in the liver and kidney GSH compared to the control, only rats that received 1200mg/kg body weight JCEE statistically decreased in the kidney. By using this website, you agree to our The mixture was allowed to cool and centrifuged at 650g for 10min to obtain the supernatant. Corra, GM., de C. Alcntara, AF. JUSTICIA PECTORALIS - Uses, Side Effects, and More - WebMD Justicia pectoralis is a flowering herb that grows in tropical areas of the Americas, including South and Central America. These compounds beyond boosting your blood concentration, thereby enhancing the transport of nutrients to various parts of the body, also boost your immune system against several infectious diseases. The indistinguishable differences of total protein in the liver and kidney of rats treated with ethanol extract of J. carnea could indicate that the plant extract did not alter protein synthetic function of the organs. DOI: https://doi.org/10.1089/ars.2007.1901. Toxicity studies of medicinal plants used in sub-Saharan Africa. Fertility leaves: Benefits and side effects, Guava Leaf Tea: Health Benefits of Guava Leaves, Coriander seeds: 18 benefits Coriandrum sativum fruits and seeds, Rapini: Nutritional facts, benefits, side effects and care. While every effort has been made to describe these plants accurately, please keep in mind that height, bloom time, and color may differ in various climates. Pot the specimen and bring it indoors to add a bright touch of color to your interiors. Stover PJ, Caudill MA. Tropical habitats mean constant moisture. The plant looks great along garden borders and near building foundations. Authors KOK and ESA performed the statistical analysis and managed the analyses of study. Tietz NW. Prof. F.O. How Justicia Betonica is effective for various diseases is listed in repertory format. The significant increase in MDA level at 1200mg/kg might be due to the presence of active secondary metabolites in the extracts that could have acted as prooxidant. However, coadministration of both extracts exerts a synergistic effecton the . Tips on how to get rid of leaf eating caterpillar. Whether added to garden beds or pots, the justicia (plant) adds a colorful tropical touch and are easy to grow. Oyenihi OR, Brooks NL, Oguntibeju OO. The weight of liver and kidney of rats were measured immediately after excising the organs and is presented in Table2. J Nat Prod 1988;51(4):804-805. In these groups, from mild to severe order; shows observable congested portal vein, the liver parenchyma showed area of harmorrhage, the morphology of the hepatocytes appear pyknotic, some show mild fat infiltration (red arrow) the sinusoids appear fibrotic with infiltration of inflammatory red cells (red arrow). In subacute study, rats were randomized into six groups of five rats per group: Group 1 (control) received distilled water, group 2, 3, 4, 5, 6 received 50, 100, 500, 800 and 1200mg/kg body weight of J. carnea ethanol extract once daily using oral gavage. Mounanga MB, Mewonob L, Angone SA. Diallo A, Gbeassor M, Vovor A, Eklu-Gadegbeku K, Aklikokou K, Agbonon A. Ethanol extracts of J. carnea leaf increased RBC, hemoglobin and platelet with significant increase (p<0.05) in groups that received higher dose (>500mg/kg b.w) of extract compared to the control. Consumption of medicinal plants has diverse therapeutic benefits and could also have toxic effect. https://doi.org/10.1016/j.biocel.2006.07.001. Justicia Carnea Leaf Benefits - Ewe eje - besthomediet The LD50 of extract was greater than 5000mg/kg body weight. View abstract. Justicia carnea needs bright, indirect light to thrive. The levels of white blood cell count, lymphocyte, granulocyte and MID could indicate that ethanol extract of J. carnea leaf pose no toxicity or sub acute inflammation to the overall defense mechanism and immunity of the experimental rats. Molecules (Basel, Switzerland), 19(12), 2144221461. Afr J Tradit Complement Altern Med. Nigeria's medicinal plant: Justicia carne (Ewe eje) - PressReader 15 Amazing benefits of brocoli juice and side effects. Karigidi is a lecturer in the Biochemistry unit of Chemical Sciences Department, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. This is attributed to the anti-hyperlipidaemic properties of the plant. 2004;19(12):16. 1. Chidubem Olovo is a biochemist and a researcher whose interest is centered on the chemistry of natural products, their pharmacological properties and how using the plant sources can improve human healthy living. -Amylase binding-interaction with JCAE was also investigated using fluorescence spectroscopy and molecular docking. Paes-Leme AA, Motta ES, De Mattos JCP. PDF Biomedical Research 2019; 30 (4): 645-654 ISSN 0970-938X - Allied Academies This later condition is termed insulin resistance. This amazing, Coriander seeds as well as the leaves are widely used as spices in flavoring foods and drinks, and, Cashew leaves: health benefits and side effects of Anacardium occidentale, Fig leaves tea: Amazing benefits and best recipes, Negro pepper: 12 health benefits of uda seed and side effects. The in-vitro . Histopathological examination of liver and kidney showed mild to severe pathological lesion in a dose dependent manner. 2010;4(8):6804 https://doi.org/10.5897/JMPR09.487. J Ethnopharmacol. Some vitamin composition of Justicia carnea leaves -Amylase binding-interaction with JCAE was also investigated using fluorescence spectroscopy and molecular docking. They can easily tolerate acidic to slightly alkaline sandy, loamy, and clay soils. 3 The plants in the family are reported to have CNS effects which are exploited in the management of epilepsy, other mental disorders, headache and fever, probably due to their sedative and analgesic properties. Another strong benefits of justicia carnea leaves is in lipid profile. Organic extract of Justicia pectoralis Jacq. and M.Sc. By entering your email address you agree to receive a daily email newsletter from Plant Care Today. According to acute toxicity grading standards, LD50 of substances greater than 5000mg/kg is practically considered non-toxic [22, 23]. Justicia Carnea is a flowering plant that may be found in our neighborhood. The aim of this study is to evaluate the safety of ethanol extract of J. carnea leaf assessing the hematology indices, organ antioxidant system and histology in healthy male wistar rats. Ewe eje is an age-old herb medically proven to act as a blood tonic which can be attributed to its nutritional composition. The appropriate dose of Justicia pectoralis depends on several factors such as the user's age, health, and several other conditions. Article Oso BJ, Oyewo EB and Oladiji AT. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD.
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